Dengue

  • Malaria and neglected tropical diseases

    Malaria is a top-ten cause of death in low-income countries, with the highest burden on children under 5. Despite significant improvement in malaria control, eradication efforts are hampered by many factors, both economic and ecological. Sustained access to funding, insecticide and drug resistance, and heterogeneity in disease outcomes and timing (due to human factors such…

  • Projected Impact of Dengue Vaccination in Yucatan, Mexico

    Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiveness of widespread vaccination campaigns has not yet been determined. We developed an agent-based dengue model representing movement of and transmission dynamics among people and mosquitoes in Yucatán, Mexico, and simulated various vaccine scenarios to evaluate effectiveness under those conditions. This…